On Expedia for a weekend stay in New York from August 27-29, we found a 3.5 star hotel in the Soho/Financial District area listed for $122, a 4-star hotel in Midtown Central for $209 and a 4-star hotel in Midtown East for $213. On Hotwire, the results looked pretty similar except we saw a 4-star in Midtown Central listed for $199 and a 4-star hotel in Midtown East for $209.
So it looks like Hotwire may still be the place to go for cheaper deals. But we like the convenience of having it done through Expedia and we suppose the Hotwire results on Betterbidding.com (the site that keeps track of blind booked hotels) would work for these Expedia results as well. The prices may vary slightly but we're sure the inventory is the same.
We'll be working on these Unpublished Rates over the next few days but if you've used this new service from Expedia, let us know in comments below how it went (i.e. what hotel you got and for how much!)