With so many places to stay, ranging from bargain-basement backpacker joints to ultra-luxe resorts, citing the city's best is sort of like pinpointing the best wedding chapel in Vegas: subjective, at best and damn near impossible. Though a few notables stand out.
One of the premier five-star hotels in Siem Reap is Hotel de la Paix, a resort that fuses modern architecture with a Khmer twist. The resort's Art Deco style distinguishes it from its competitors, as does its commitment to responsible consumption and support of local welfare organizations. Who knows how much of this altruism is PR fluff and what is substantial.
Still, visiting a city that exhibits both ancient and modern opulence also sheds light on those who have been left out (beggars and land mine victims line the streets of Siem Reap). So while your enjoying a customized spa treatment on the rooftop terrace, knowing a portion of the proceeds goes toward helping the folks outside the gates might help ease your conscience and put your mind on the path to relaxation.
Right now, the hotel's Arts Lounge also features a memorial to Khmer Rouge victims and at Christmastime, the hotel runs a toy drive to benefit children at the local hospital.